A case-control pilot study of low-intensity IVF in good-prognosis patients

A case-control pilot study of low-intensity IVF in good-prognosis patients, Gleicher, N, Reprod BioMed Online, 2012

Dr. Daiter of Central New Jersey Low Cost IVF mini and natural cycle ivf provides a summary of this research article on low cost ivf

Target: good prognosis IVF patients

Goal: to determine how reproductive success compares between good prognosis patients undergoing low-intensity IVF (LI-IVF) to similar patients undergoing conventional IVF

A case control pilot study involving 14 first LI-IVF and 14 standard IVF cycles in women with normal ovarian reserves, the mild stimulation protocol for LI-IVF involved Clomiphene citrate augmented with low dose gonadotropins, with similar numbers of embryos transferred the conventional IVF demonstrated better odds for pregnancy (cumulative pregnancy rates for conventional IVF 63% and LI-IVF 21%), and the cost for the conventional IVF was not statistically different from the cost of LI-IVF.

Conclusion: In this small pilot study, LI-IVF cycles were clinically inferior to conventional IVF in terms of reproductive outcome and the LI-IVF cycles were similar in cost, so they should be considered “experimental.”


Dr. Daiter of Central New Jersey Low Cost IVF mini and natural cycle ivf reviews of this website information

Dr. Norbert Gleicher is a renowned infertility expert and the CEO and Chairman of GynCor.  GynCor Inc is a so-called physician practice management company that owns or operates roughly 26 infertility clinics, known as the Centers for Human Reproduction (CHR) in California, Delaware, Florida, Illinois, Indiana, Maryland, New Jersey and Virginia.
In this small pilot study from 2012 the reproductive advantage of LI-IVF protocols were not clear and therefore they were considered experimental.  Since this time, the minimal stimulation protocols for IVF have developed enormously and success rates have grown to now reportedly compete favorably with conventional IVF.
Mini IVF is controversial and some still say it is experimental.  Patients considering this treatment should be aware of this and that success rates are likely to continue to climb as progress is made in the available technology and protocols.

There is currently a division of the Center for Human Reproduction (CHR) known as “ECO-IVF” that operates with different practice patterns and protocols than within their conventional IVF divisions, where at CHR patients using ECO-IVF rather than “regular IVF” may take longer to get pregnant without any cost benefits.  For more information on this program: https://www.centerforhumanreprod.com/services/discountprograms/ecolvf/


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